Monday, May 21, 2007

Olfactory Ensheathing Cells.

Yesterday was spent mostly in the midst of an extensive amount of Neural Degeneration. Why won't CNS neurones regenerate when PNS ones will, and what can we do to stop this? And, I read about some very interesting cell types, the olfactory-ensheathing-cell. The injured CNS provides an inhibitory environment to axon regeneration, but the OECs may be able to ensheath the axons and provide a permissive environment for axon growth by integrating with astrocytes in the brain. It's all quite exciting. In mouse studies they've helped axons regenerate across a cut spinal cord and led to some functional improvement. Clinical trials have started so watch this space for developments.

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